CD13 Immunostain, Technical Component Only
Use
CD13, also known as cluster of differentiation 13, serves key functions in peptide metabolism, particularly within brush border membranes of the small intestine, renal proximal tubules, and placenta. It plays a crucial role in cell growth, differentiation, and phagocytosis. CD13 is typically expressed on myeloid lineage cells, including granulocytes and monocytes, and is found on certain non-hematolymphoid cells such as endothelial cells and fibroblasts, as well as in a soluble form in plasma. This immunostain is a valuable marker for identifying myeloid lineage, particularly in the context of acute leukemias.
Special Instructions
Not provided.
Limitations
The technical performance only includes the stain without pathologist interpretation, so a separate pathology consultation is recommended for results interpretation. Use caution regarding the age and storage conditions of paraffin sections, as they can significantly impact immunoreactivity. Environmental factors can alter the effectiveness of glass slide charges, consequently affecting staining quality. For optimal results, paraffin sections should be freshly cut within six weeks, and slides should be stored out of humidity and heat.
FDA ApprovedNew York Approved
Methodology
Immunoassay (IHC)
Biomarkers
CD13
Protein
LOINC Codes
- Order only;no result
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
Immunostain Technical Only Envelope
Collection Instructions
Formalin-fixed, paraffin-embedded tissue block or 2 unstained, positively charged glass slides (25- x 75- x 1-mm), sections 4-microns thick
Storage Instructions
Ambient (preferred); Refrigerated
Causes for Rejection
Wet/frozen tissue, cytology smears, nonformalin fixed tissue, nonparaffin embedded tissue, noncharged slides, ProbeOn slides, Snowcoat slides