CD15 Immunostain, Technical Component Only
Use
The CD15 immunostain is utilized for phenotyping leukemias and lymphomas. CD15 (cluster of differentiation 15) is expressed in granulocytes and can be expressed in malignant lymphomas and acute myeloid leukemias. Reed-Sternberg cells in classical Hodgkin lymphoma typically express CD15 and CD30, making this test valuable in diagnosing and differentiating these conditions.
Special Instructions
This test is for the technical component only and does not include pathologist interpretation. If pathologist interpretation is required, a separate order for a Pathology Consultation (PATHC) is necessary. Technical component-only stains should not be ordered with PATHC, as they will be canceled if ordered together. For digital image access, orders must be placed electronically to view the images online.
Limitations
The CD15 Immunostain, Technical Component Only, does not include pathologist interpretation. It is crucial that interpretation is performed in conjunction with the patient's clinical history and other diagnostic tests by a qualified pathologist. The test performance may be affected by factors such as age of the paraffin section and the quality of the glass slides, which can alter staining outcomes. Proper storage and handling of slides are essential to maintain staining quality.
FDA ApprovedNew York Approved
Methodology
Immunoassay (IHC)
Biomarkers
LOINC Codes
- Order only;no result
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
Immunostain Technical Only Envelope
Collection Instructions
Use formalin-fixed, paraffin-embedded tissue blocks or 2 unstained, positively charged glass slides (25- x 75- x 1-mm) per test ordered; sections should be 4 microns thick. Attach both the green pathology address label and the pink Immunostain Technical Only label to the transport container.
Storage Instructions
Storage conditions for slides are critical: minimize storage time after unpackaging, limit exposure to high humidity and heat, and reduce exposure to plastics.
Causes for Rejection
Wet/frozen tissue, cytology smears, nonformalin fixed tissue, nonparaffin embedded tissue, noncharged slides, ProbeOn slides, Snowcoat slides will be rejected.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Ambient preferred |
| Refrigerated | Allowed |