Cranberry, IgE, Serum
Use
The test is useful for establishing the diagnosis of an allergy to cranberry, defining the allergen responsible for eliciting signs and symptoms, identifying allergens responsible for allergic responses or anaphylactic episodes, confirming sensitization prior to immunotherapy, and investigating the specificity of allergic reactions to insect venom allergens, drugs, or chemical allergens. It is not useful for determining if residual clinical sensitivity exists after immunotherapy or when medical management does not rely on allergen specificity identification.
Special Instructions
For a listing of allergens available for testing, see the Allergens - Immunoglobulin E (IgE) Antibodies documentation. If not ordering electronically, complete and send an Allergen Test Request (T236) with the specimen. Gross hemolysis and gross lipemia are acceptable for testing. Authorized users can access detailed fee information through the Test Prices resource.
Limitations
Testing for IgE antibodies may show false positive results in patients with markedly elevated serum IgE due to nonspecific binding to allergen solid phases. Some individuals with clinically insignificant sensitivity to allergens may have measurable levels of IgE antibodies in serum. Test results must be interpreted in the clinical context. It is important to note that this test was developed by Mayo Clinic and has not been cleared or approved by the US Food and Drug Administration.
New York Approved
Methodology
Immunoassay (FEIA)
Biomarkers
LOINC Codes
- 7262-9
- 7262-9
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL for every 5 allergens requested
Minimum Volume
(0.05 mL x number of allergens) + 0.25 mL dead space
Container
Preferred: Serum gel; Acceptable: Red top; Submission: Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Storage Instructions
Refrigerated preferred for up to 14 days or frozen for 90 days.
Causes for Rejection
Gross hemolysis or lipemia is acceptable.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 90 days |