Cryptococcus Antigen Titer, Lateral Flow Assay, Urine
Use
Aiding in the diagnosis of infection with Cryptococcus neoformans or Cryptococcus gattii. Cryptococcosis is an invasive fungal infection that can affect the lungs and central nervous system (CNS), particularly in patients with immunosuppressive conditions like AIDS. The presence of cryptococcal antigen (CrAg) in urine is suggestive of such infections. However, this test should not be used as a test of cure.
Special Instructions
This test is not orderable as a standalone test and is only available as a reflex. For more information see ULFA / Cryptococcus Antigen Screen, Lateral Flow Assay, Random, Urine.
Limitations
A negative result does not preclude the diagnosis of cryptococcosis, particularly if only a single specimen has been tested. Extremely high concentrations of cryptococcal antigen can result in weak-positive or false-negative results. Patients with trichosporonosis or Capnocytophaga species infection may yield false-positive results. Monitoring CrAg titers should not be used as a test of cure, as low-level titers may persist post-treatment.
New York Approved
Methodology
Immunoassay (Lateral Flow)
Biomarkers
LOINC Codes
- 93766-4
- 93766-4
Result Turnaround Time
1-4 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
1 mL
Minimum Volume
0.5 mL
Container
Plastic, 10-mL urine tube
Collection Instructions
Collect a random urine specimen. No preservative.
Causes for Rejection
Gross hemolysis; Turbid; Colored
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 14 days |