Desmin Immunostain, Technical Component Only
Use
This test helps in the identification of striated and smooth muscle cells, as well as tumors derived from these cell types, such as leiomyosarcomas and rhabdomyosarcomas. Desmin is an intermediate filament protein found in muscle cells, and its presence can indicate myogenic origin in neoplastic tissues.
Special Instructions
Not provided.
Limitations
The test only performs the staining process, and interpretation must be done by a qualified pathologist using the patient's clinical history and other diagnostic tests. The age of a cut paraffin section can affect immunoreactivity, and stability thresholds vary among literature. Environmental factors can affect slide chemistry, leading to inconsistent staining.
FDA ApprovedNew York Approved
Methodology
Immunoassay (IHC)
Biomarkers
Desmin
Protein
LOINC Codes
- Order only;no result
- Bill only; no result
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
Immunostain Technical Only Envelope
Causes for Rejection
Wet/frozen tissue, Cytology smears, Nonformalin fixed tissue, Nonparaffin embedded tissue, Noncharged slides, ProbeOn slides, Snowcoat slides
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Ambient (preferred) |
| Refrigerated | Refrigerated |