Epithelia Panel #2, Serum
Use
The Epithelia Panel #2 is useful for establishing a diagnosis of allergies to guinea pig, hamster, mouse, rabbit, or rat. It identifies allergens responsible for allergic responses or anaphylactic episodes, confirms sensitization before starting immunotherapy, and explores the specificity of allergic reactions to insect venom, drugs, or chemicals. The test measures IgE antibodies in serum, indicating the immune response to allergens associated with allergic diseases.
Special Instructions
This test uses a pooled allergen reagent, reported with a single qualitative class result and concentration. It's not useful for patients previously treated with immunotherapy if determining residual clinical sensitivity is needed or where allergen specificity doesn't impact medical management. For a listing of allergens available for testing, refer to the Allergens - Immunoglobulin E (IgE) Antibodies document. Submission requires the use of a plastic vial and may require a completed Allergen Test Request form if not ordered electronically.
Limitations
This test provides a single result for the Epithelia Panel, but it cannot identify individual allergen responses within the panel. Further testing is required following a positive result to differentiate between individual allergens. False positives may occur in patients with markedly elevated serum IgE (>2500 kU/L). Despite measurable levels of IgE antibodies, some results may not indicate significant clinical sensitivity, necessitating cautious interpretation within the clinical context.
FDA ApprovedNew York Approved
Methodology
Immunoassay (CLIA)
Biomarkers
LOINC Codes
- 71370-1
- 71370-1
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL for every 5 allergens requested
Minimum Volume
0.3 mL
Container
Serum gel (preferred) or Red top; submission in Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Causes for Rejection
Rejection conditions include gross hemolysis and gross lipemia.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 90 days |