Ethyl Glucuronide Confirmation, Chain of Custody, Random, Urine
Use
This test is used to monitor abstinence in clinical and justice system settings by detecting ethyl glucuronide (EtG) and ethyl sulfate (EtS), which are direct biomarkers of ethanol. EtG and EtS are minor metabolites detectable in urine following alcohol consumption, enabling detection up to 5 days after intake. It is utilized where definitive diagnoses are needed based on test results, such as for legal or disciplinary actions in court. Chain of custody is vital to ensure the specimen's integrity and validity under legal scrutiny.
Special Instructions
The test requires a chain-of-custody procedure to maintain specimen integrity. It's performed using a chain-of-custody kit that includes necessary containers, seals, and documentation. Additional chain-of-custody forms must be submitted if not ordering electronically. This test is specifically designed for use in legal scenarios where the specimen handling needs documentation to validate the chain-of-custody process.
Limitations
Results should be interpreted considering potential alcohol exposure from non-alcoholic sources like hand sanitizers or mouthwash, which might contribute to detectable levels of EtG and EtS. Factors like upper respiratory infections can affect EtG results. The test detects EtG and EtS in urine, considering concentrations of 500 ng/mL for immunoassays and 250 ng/mL/100 ng/mL for LC-MS/MS, respectively. False positives from incidental exposure should be considered.
New York Approved
Methodology
Mass Spectrometry (LC-MS/MS)
Biomarkers
LOINC Codes
- 93705-2
- 58425-0
- 93706-0
- 58378-1
- 77202-0
- 59462-2
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
5 mL
Minimum Volume
2.5 mL
Container
Chain-of-custody kit containing the specimen containers, seals, and documentation
Collection Instructions
Collect specimen in the provided container, seal, and submit with the associated documentation to satisfy the legal requirements for chain-of-custody testing.
Causes for Rejection
Gross hemolysis - OK, Gross icterus - OK
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 28 days |
| Refrigerated | 28 days |
| Frozen | 28 days |