Fatty Acid Profile, Comprehensive (C8-C26), Serum
Use
This test is useful for monitoring patients undergoing diet therapy for mitochondrial or peroxisomal disorders, which may induce essential fatty acid deficiency due to restricted fat intake. It is also used for monitoring the treatment of essential fatty acid deficiency and the response to provocative tests like fasting and loading tests. Additionally, the test provides comprehensive information regarding mitochondrial and peroxisomal fatty acid metabolism and the patient's nutritional status.
Special Instructions
Not provided.
Limitations
This test is not the recommended initial screening for possible peroxisomal disorders, single-enzyme defects of peroxisomal metabolism, or peroxisomal biogenesis disorders. Alternative tests like POXP / Fatty Acid Profile, Peroxisomal (C22-C26), Plasma or POX / Fatty Acid Profile, Peroxisomal (C22-C26), Serum are preferable for such cases. Specimen may be rejected due to gross lipemia. Serum stability is best preserved by freezing, but it can be refrigerated for limited time storage.
New York Approved
Methodology
Mass Spectrometry (GC-MS)
Biomarkers
LOINC Codes
- 43674-1 - FA comp C8-C26 Pnl SerPl
- 35145-2 - Octanoate SerPl-sCnc
- 35147-8 - Decenoate SerPl-sCnc
- 35146-0 - Decanoate SerPl-sCnc
- 35151-0 - Lauroleate SerPl-sCnc
- 35150-2 - Laurate SerPl-sCnc
- 35148-6 - Tdecadienoate SerPl-sCnc
- 35158-5 - Myristoleate SerPl-sCnc
- 35157-7 - Myristate SerPl-sCnc
- 35154-4 - Hexadecadienoate SerPl-sCnc
- 35155-1 - Hexadecenoate SerPl-sCnc
- 35162-7 - Palmitoleate SerPl-sCnc
- 35161-9 - Palmitate SerPl-sCnc
- 35163-5 - G-Linolenate SerPl-sCnc
- 35164-3 - A-Linolenate SerPl-sCnc
- 35165-0 - Linoleate SerPl-sCnc
- 35166-8 - Oleate SerPl-sCnc
- 35167-6 - Vaccenate SerPl-sCnc
- 35149-4 - Octadecanoate SerPl-sCnc
- 35173-4 - EPA SerPl-sCnc
- 35168-4 - AA SerPl-sCnc
- 35172-6 - Mead acid SerPl-sCnc
- 35171-8 - Homo-G Linolenate SerPl-sCnc
- 35169-2 - Arachidate SerPl-sCnc
- 35174-2 - DHA SerPl-sCnc
- 35181-7 - Docosapentaenate w6 SerPl-sCnc
- 35180-9 - DPA SerPl-sCnc
- 35182-5 - Docosatetraenoate SerPl-sCnc
- 35160-1 - Docosenoate SerPl-sCnc
- 30194-5 - VLCFA C22:0 SerPl-sCnc
- 35170-0 - Nervonate SerPl-sCnc
- 30195-2 - VLCFA C24:0 SerPl-sCnc
- 33036-5 - VLCFA C26:1 SerPl-sCnc
- 30197-8 - VLCFA C26:0 SerPl-sCnc
- 22761-1 - Pristanate SerPl-sCnc
- 22671-2 - Phytanate SerPl-sCnc
- 35411-8 - Trienoate/AA SerPl-sRto
- 35175-9 - Sat FA SerPl-sCnc
- 35176-7 - Monounsat FA SerPl-sCnc
- 35177-5 - Polyunsat FA SerPl-sCnc
- 35178-3 - w3 FA SerPl-sCnc
- 35179-1 - w6 FA SerPl-sCnc
- 24461-6 - FA SerPl-sCnc
- 59462-2 - Clinical biochemist review
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL
Minimum Volume
0.15 mL
Container
Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Patient Preparation
Fasting for 12 hours is required for nutritional assessment. Avoid alcohol for 24 hours before collection.
Storage Instructions
Preferred storage is frozen for up to 92 days; refrigerated for up to 72 hours is acceptable.
Causes for Rejection
Rejects if gross lipemia is observed.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 72 hours |
| Frozen | 92 days |