Fluphenazine (Prolixin), Serum
Use
This test is used to measure the levels of Fluphenazine, also known as Prolixin, in the serum. Fluphenazine is an antipsychotic medication used primarily in the management of schizophrenia. Monitoring its levels can help in optimizing dosage, ensuring therapeutic efficacy, and monitoring for potential toxicity. It is crucial for tailoring the treatment plan in patients on long-term Fluphenazine therapy to maintain the drug concentrations within the therapeutic range.
Special Instructions
Ensure proper specimen collection to avoid rejection. Use the specified red top tube for collection and follow strict handling protocols to maintain specimen integrity for accurate results.
Limitations
This test has limitations including possible interference due to hemolysis, lipemia, and icterus which can cause specimen rejection. It may not detect low levels of the drug in patients with poor compliance or those who metabolize the drug more rapidly. Cross-reactivity with other medications is also a potential limitation, requiring careful interpretation in the context of the patient's overall medication profile.
New York Approved
Methodology
Mass Spectrometry (LC-MS/MS)
Biomarkers
LOINC Codes
- 3650-9
- 3650-9
Result Turnaround Time
7-9 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
3 mL
Minimum Volume
0.5 mL
Container
Plastic vial
Collection Instructions
Centrifuge and aliquot 3 mL of serum into a plastic vial. Send refrigerate.
Storage Instructions
Refrigerate for up to 14 days, ambient for 72 hours, or freeze for up to 180 days.
Causes for Rejection
Gross hemolysis, gross lipemia, gross icterus, specimens other than serum collected in red top tube, plasma or whole blood collected in tubes other than sodium heparin or EDTA, serum or plasma gel tubes.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 72 hours |
| Refrigerated | 14 days |
| Frozen | 180 days |