Fluvoxamine (Luvox)
Use
Fluvoxamine measurement is key in evaluating therapeutic levels for managing patients undergoing treatment with this medication. It helps optimize drug dosing and monitor patient compliance. Fluvoxamine is an antidepressant elevating neurotransmitter action and used in treating obsessive-compulsive disorder as well as major depressive disorder. Monitoring serum or plasma levels ensures effectiveness while avoiding toxicity.
Special Instructions
Important to use the correct tube type: green-top sodium heparin for plasma or plain red-top for serum. Specimen transport is critical — refrigerate samples and avoid using gel tubes to maintain specimen integrity. Timely sample receipt guarantees accurate analysis and reporting.
Limitations
Specimen integrity can be compromised if gel tubes are used, as they are not acceptable for plasma or serum collection. Also, mild hemolysis, lipemia, or icterus do not seem to impact the analysis, but any extraneous interference should be avoided for precision. Changes in matrix composition can cause assay variability, influencing fluvoxamine quantification. Therefore, submitted specimen volume is essential to ensure comprehensive analyses in repeat or confirmatory testing.
New York Approved
Methodology
Mass Spectrometry (HPLC-UV)
Biomarkers
LOINC Codes
- 10988-4
- 10988-4
Result Turnaround Time
3-7 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
3 mL
Minimum Volume
0.6 mL
Container
Plastic vial
Collection Instructions
Draw blood in a green-top sodium heparin tube(s), plasma gel tube is not acceptable. Spin down and send 3 mL of plasma refrigerated in a plastic vial.
Storage Instructions
Refrigerate samples to maintain stability.
Causes for Rejection
Use of gel tubes for plasma or serum is unacceptable.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 72 hours |
| Refrigerated | 7 days |
| Frozen | 180 days |