Garlic, IgE, Serum
Use
This test is useful for establishing a diagnosis of allergy to garlic. It helps in defining the allergen responsible for eliciting signs and symptoms in patients. Additionally, it serves to identify allergens responsible for allergic responses and anaphylactic episodes. Testing for IgE antibodies is particularly significant in confirming sensitization before beginning immunotherapy and in investigating the specificity of allergic reactions to various allergens including insect venom, drugs, or chemical allergens.
Special Instructions
If not ordering electronically, complete, print, and send an Allergen Test Request form (T236) with the specimen. For more information on available allergens for testing, see the Allergens - Immunoglobulin E (IgE) Antibodies PDF where further allergens are listed.
Limitations
Testing for IgE antibodies is not useful in patients who have been previously treated with immunotherapy to determine if residual clinical sensitivity exists. It is also not useful in patients when the medical management does not depend upon identification of allergen specificity. There is a potential for false-positive results in patients with markedly elevated serum IgE (>2500 kU/L) due to nonspecific binding to allergen solid phases.
Methodology
Immunoassay (Fluorescence Enzyme Immunoassay (FEIA))
Biomarkers
LOINC Codes
- 6122-6
- 6122-6
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL for every 5 allergens requested
Minimum Volume
For 1 allergen: 0.3 mL; For more than 1 allergen: (0.05 mL x number of allergens) + 0.25 mL deadspace
Container
Preferred: Serum gel; Acceptable: Red top; Submission container: Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Causes for Rejection
Gross hemolysis: OK; Gross lipemia: OK
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 90 days |
