Gentamicin, Peak, Serum
Use
Gentamicin is an antibiotic used to treat life-threatening blood infections caused by gram-negative bacilli. This test is useful for monitoring the adequacy of drug clearance during gentamicin therapy, helping to ensure the drug reaches therapeutic levels without exceeding toxic concentrations.
Special Instructions
Not provided.
Limitations
Patient samples containing the drug sisomicin will yield falsely elevated values for gentamicin. High concentrations of penicillins or cephalosporins can inactivate gentamicin in vitro under certain conditions. Samples should be assayed immediately if other antibiotics are used. Heterophile antibodies may cause erroneous results.
Methodology
Immunoassay (Turbidimetric Immunoassay)
Biomarkers
Gentamicin
Analyte
LOINC Codes
- 3663-2 - Gentamicin Peak SerPl-mCnc
- 3663-2 - Gentamicin Peak SerPl-mCnc
Result Turnaround Time
1 day
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL
Minimum Volume
0.25 mL
Container
Plastic vial
Collection Instructions
Serum gel tubes should be centrifuged within 2 hours of collection. Red top tubes should be centrifuged and serum aliquoted into a plastic vial within 2 hours.
Causes for Rejection
Gross hemolysis
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 72 hours |
| Refrigerated | 7 days |
| Frozen | 14 days |
