Goldenrod, IgE, Serum
Use
Testing for IgE antibodies can assist in establishing a diagnosis of an allergy to goldenrod and defining the specific allergens responsible for allergic responses. It is useful in confirming sensitization prior to immunotherapy and investigating allergic reactions to various allergens, including insect venom, drugs, or chemicals. However, it is not useful for determining residual clinical sensitivity in patients previously treated with immunotherapy or when clinical management does not depend on allergen specificity.
Special Instructions
For a comprehensive list of available allergens, refer to the available Allergens - Immunoglobulin E (IgE) Antibodies guide. If the test is not ordered electronically, an Allergen Test Request Form (T236) should be completed and sent with the specimen.
Limitations
Patients with clinically insignificant sensitivity to allergens may still have measurable serum IgE levels, possibly leading to false positives. Test results should always be interpreted within the clinical context, considering IgE levels might be elevated due to non-specific binding to solid phases in patients with significantly elevated serum IgE (>2500 kU/L).
Methodology
Immunoassay (Enzyme Immunoassay)
Biomarkers
LOINC Codes
- 6128-3
- 6128-3
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL for every 5 allergens requested
Minimum Volume
0.3 mL for 1 allergen. For more than 1 allergen: (0.05 mL x number of allergens) + 0.25 mL deadspace
Container
Preferred: Serum gel; Acceptable: Red top. Submission: Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 90 days |
