Heavy Metals, Nails
Use
Detection of nonacute arsenic, mercury, and lead exposure using nail specimens; provides indicator of chronic exposure via keratin-bound metals accumulated in nails, reflecting exposure over previous months.
Special Instructions
Not provided.
Limitations
Exposure reflected is historical (e.g., nails grow ~0.1 inch/month, distal clipping reflects exposure ~6 months prior); nail results may be affected by external contamination (especially lead), and reference intervals may not be established for pediatric age groups.
Methodology
Mass Spectrometry (ICP-MS/MS)
Biomarkers
Arsenic
AnalyteLead
AnalyteMercury
Analyte
LOINC Codes
- 94574-1 - Heavy Met Pnl Nail
- 8157-0 - Arsenic Nail-mCnt
- 8204-0 - Mercury Nail-mCnt
- 8202-4 - Lead Nail-mCnt
Result Turnaround Time
2-14 days
Related Documents
For more information, please review the documents below
Specimen
Nail
Volume
0.2 g
Minimum Volume
0.05 g
Container
Hair and Nails Collection Kit (T565)
Collection Instructions
Prepare and transport specimen per the instructions in the kit; clippings taken from all 10 fingernails or toenails; indicate source of nails (fingernails or toenails) if known.
Causes for Rejection
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.