Hemoglobin Electrophoresis Interpretation
Use
This test provides interpretation for the results of hemoglobin electrophoresis, aiding in the diagnosis and classification of hemoglobin disorders including thalassemias and hemoglobin variants. It is used for identifying variations in hemoglobin types that might suggest disorders like sickling disorders, thalassemias, and other hemoglobinopathies. Commonly identified abnormalities include an increase in HbA2, indicative of beta-thalassemia minor, and various other hemoglobin variants such as Hb S, C, E, and others.
Special Instructions
Not provided.
Limitations
Some hemoglobin disorders, particularly common alpha thalassemia conditions, may not be detected by standard screening methods and could require additional reflex testing. Transfusions, recent or historical, may affect the detection of certain hemoglobin variants. Proper communication regarding previous therapies or transfusion history enhances the accuracy and relevance of the testing results. Specific therapies like hydroxyurea may produce artefacts in protein studies, which necessitates careful interpretation.
Methodology
Other
Biomarkers
LOINC Codes
- 13514-5 - Hgb Fract Bld Elph-Imp
- 49316-3 - Hgb Fract Bld Elph-Imp
Result Turnaround Time
2-25 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
Not provided
Minimum Volume
Not provided
Container
EDTA
Storage Instructions
Refrigerated
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 7 days |
