Hepatitis B Core (HBc) Immunostain, Technical Component Only
Use
The test is useful for aiding in the identification of hepatitis B infection, particularly in the chronic active state. The hepatitis B nucleocapsid contains 2 serologically distinct antigens, core and envelope antigens, surrounded by an outer envelope-hepatitis B virus surface antigen. The core antigen is more commonly present in chronic active hepatitis compared to the surface antigen, which is found in the carrier state.
Special Instructions
This test includes only the technical performance of the stain and does not include a pathologist interpretation. If ordered with PATHC / Pathology Consultation, the technical component stains will be canceled. Attach the 'Attention Pathology' label and the 'Immunostain Technical Only' label to the transport container.
Limitations
This test does not provide pathologist interpretation, only the technical performance of the stain. Interpretation should be performed in the context of the patient's clinical history and other diagnostic tests by a qualified pathologist. The age of a cut paraffin section can affect immunoreactivity, and stability thresholds vary widely among published literature and are antigen dependent. The charge on glass slides can be affected by environmental factors, which may alter staining consistency.
FDA ApprovedNew York Approved
Methodology
Immunoassay (IHC)
Biomarkers
LOINC Codes
- Order only;no result
- Bill only; no result
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
Immunostain Technical Only Envelope
Collection Instructions
Formalin-fixed, paraffin-embedded tissue block or 2 unstained, positively charged glass slides (25- x 75- x 1-mm) per test ordered; sections 4-microns thick.
Storage Instructions
Attach the green 'Attention Pathology' address label (T498) and the pink Immunostain Technical Only label included in the kit to the outside of the transport container.
Causes for Rejection
Wet/frozen tissue, cytology smears, nonformalin fixed tissue, nonparaffin embedded tissue, noncharged slides, ProbeOn slides, Snowcoat slides