Hexagonal Lupus Anticoagulant, Plasma
Use
The test is used for confirming or excluding the presence of a lupus anticoagulant, in conjunction with other appropriate coagulation tests. It helps differentiate between deficiencies or inhibitors of specific coagulation factors and lupus anticoagulant inhibitors, and evaluates a prolonged activated partial thromboplastin time resulting from inhibition. Lupus anticoagulants are immunoglobulins that interfere with specific coagulation factor-phospholipid interactions, causing prolongation of phospholipid-dependent clotting time tests.
Special Instructions
Only orderable as part of a reflex. For more information see Thrombophilia Profile, Bleeding Diathesis Profile, Disseminated Intravascular Coagulation/Intravascular Coagulation and Fibrinolysis (DIC/ICF) Profile, and Lupus Anticoagulant Profile.
Limitations
Hexagonal lupus anticoagulant testing is not interfered with by hemolysis (hemoglobin 10,000 platelets/mcL) and abnormally low factor II activities (below 50%) may interfere with interpretation, potentially resulting in false-negative results.
Methodology
Other
Biomarkers
LOINC Codes
- 96267-0
- 96267-0
Result Turnaround Time
2-4 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
Not provided
Minimum Volume
Not provided
Causes for Rejection
Gross hemolysis, gross lipemia, gross icterus
Stability Requirements
| Temperature | Period |
|---|---|
| Frozen | 60 days |
