Histamine, Whole Blood
Use
Histamine testing in whole blood is used to assess histamine levels in the body, which can be indicative of allergic reactions, mastocytosis, or other histamine-related disorders. Measuring the concentration of histamine in blood helps in diagnosing and managing conditions where histamine plays a crucial role, like allergies, anaphylaxis, or histamine intolerance.
Special Instructions
This test involves critical handling procedures; specimens must be frozen immediately after collection to prevent degradation. Separate specimens should be submitted when multiple tests are ordered to ensure accuracy and prevent cross-contamination.
Limitations
The test has certain constraints such as the necessity of immediate freezing after sample collection to ensure the stability of the histamine levels. Any delay in processing or inappropriate handling could lead to inaccurate results. Additionally, environmental histamine exposure prior to sample collection may affect the results, thus careful consideration of external factors is necessary.
New York Approved
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 46436-2
- 46436-2
Result Turnaround Time
3-11 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
1 mL
Minimum Volume
0.5 mL
Container
Plastic vial
Collection Instructions
1. Draw blood in a green-top tube (sodium or lithium heparin). 2. Aliquot 1 mL well mixed whole blood into a plastic vial. 3. Freeze specimen.
Storage Instructions
Specimens must be submitted frozen.
Causes for Rejection
Ambient or refrigerated samples
Stability Requirements
| Temperature | Period |
|---|---|
| Frozen | 180 days |