House Dust/H-S Lab, IgE, Serum
Use
The test is useful for establishing a diagnosis of allergy to house dust/H-S lab. It helps define the allergen responsible for eliciting allergic reactions and confirms sensitization prior to immunotherapy. By identifying allergens responsible for allergic response or anaphylactic episodes, it can investigate specificity of allergic reactions to insect venom, drugs, or chemical allergens. Testing for IgE antibodies is not useful in patients treated with immunotherapy for residual clinical sensitivity or when medical management doesn't depend on identification of allergen specificity.
Special Instructions
For ordering, if not done electronically, complete and print the Allergen Test Request form (T236) with the specimen. A listing of allergens available for testing can be found in the provided PDF link.
Limitations
Testing may result in false positives for IgE antibodies in patients with markedly elevated serum IgE (>2500 kU/L) due to nonspecific binding. Additionally, some individuals with clinically insignificant sensitivity to allergens may have measurable levels of IgE antibodies, requiring test results to be interpreted in the clinical context.
Methodology
Immunoassay (FEIA)
Biomarkers
LOINC Codes
- 7425-2
- 7425-2
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL for every 5 allergens requested
Minimum Volume
0.3 mL for 1 allergen (0.05 mL x number of allergens) + 0.25 mL deadspace for more than 1 allergen
Container
Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Causes for Rejection
Gross hemolysis and gross lipemia are acceptable.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 90 days |
