Hydrocodone with Metabolite Confirmation, Random, Urine
Use
This test is useful for the detection and quantification of hydrocodone, norhydrocodone, and hydromorphone in urine. These compounds are beneficial for assessing compliance with prescribed hydrocodone therapy, detecting hydrocodone misuse, or monitoring potential exposure to various opiates. The detection of these metabolites indicates exposure within 2 to 3 days prior to specimen collection. Positive results are accompanied by a quantitative result, useful in understanding recent ingestion patterns.
Special Instructions
Not provided.
Limitations
Other drugs in the opioid class, such as fentanyl, meperidine, methadone, and opiate antagonists like naloxone, are not detected by this test. The presence of pharmaceutical impurities from medications such as oxycodone or hydromorphone could lead to trace observations of hydrocodone. Interpretation requires careful assessment to avoid diagnostic confusion related to improper specimen collection, handling, or inappropriate test selection.
New York Approved
Methodology
Mass Spectrometry (LC-MS/MS)
Biomarkers
Hydrocodone
AnalyteHydromorphone
AnalyteNorhydrocodone
Analyte
LOINC Codes
- 74760-0 - HYDROcodone + metabs Pnl Ur Cfm
- 16252-9 - HYDROcodone Ur Cfm-mCnc
- 16998-7 - HYDROmorphone Ur Cfm-mCnc
- 69050-3 - Toxicologist review
- 61422-2 - Norhydrocodone Ur Cfm-mCnc
Result Turnaround Time
2-5 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
3 mL
Minimum Volume
2.5 mL
Container
Plastic, 5-mL tube
Collection Instructions
Collect a random urine specimen. No preservative. No specimen substitutions. Submitting less than 1 mL will compromise testing.
Storage Instructions
Refrigerate (preferred) for 28 days, or keep ambient for 14 days, or frozen for 28 days.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 28 days |
| Frozen | 28 days |