Immunoglobulin A (IgA) Heavy and Light Chain (HLC) Pairs, Kappa and Lambda with Ratio

Use

The Immunoglobulin A (IgA) Heavy and Light Chain (HLC) Pairs test measures the kappa and lambda chains along with their ratio, which can aid in the assessment of clonal plasma cell disorders. The kappa and lambda light chain ratio can suggest the presence of a monoclonal protein, which is often associated with conditions such as multiple myeloma or other plasma cell dyscrasias. An elevated IgA kappa to lambda ratio may suggest a kappa clone proliferation, while a low ratio may indicate a lambda clone.