Insulin-Like Growth Factor 1 and Insulin-Like Growth Factor-Binding Protein 3 Growth Panel, Serum
Use
This test is useful for diagnosing growth disorders and adult growth hormone deficiency. It aids in monitoring recombinant human growth hormone treatment. Insulin-like growth factor binding protein 3 serves as a possible adjunct to IGF1 and growth hormone levels in the diagnosis and follow-up of acromegaly and gigantism.
Special Instructions
Not provided.
Limitations
IGF1 reference values are highly age-dependent, and results should be interpreted considering the patient's age. IGF1 assays vary across platforms, which might make direct comparison problematic. Discrepant results can occur due to liver or kidney disease, and heterophile antibodies may rarely interfere with the IGFBP3 assay, causing erroneous results.
New York Approved
Methodology
Mass Spectrometry (LC-MS/MS)
Biomarkers
LOINC Codes
- 2483-6 - IGF BP3 SerPl-mCnc
- 2484-4 - IGF-I SerPl-mCnc
- 73561-3 - IGF-I Z-score SerPl
Result Turnaround Time
4-8 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
2 Plastic vials
Collection Instructions
Centrifuge within 1 hour of collection. Aliquot into 2 plastic vials in equal portions.
Causes for Rejection
Gross hemolysis
Stability Requirements
| Temperature | Period |
|---|---|
| Frozen | 14 days |