Keratin (OSCAR) Immunostain, Technical Component Only
Use
The OSCAR cytokeratin antibody covers a wide spectrum of molecular weights and is similar in expression pattern to CAM5.2, but with greater coverage of high molecular weight range such as squamous epithelium. It is diagnostically significant as antikeratin antibodies are typically used in panels to determine the cell lineage of poorly differentiated malignant tumors.
Special Instructions
Not provided.
Limitations
This test does not include pathologist interpretation, only the technical performance of the stain. Interpretation should be performed in the context of the patient's clinical history and other diagnostic tests by a qualified pathologist. Age and environmental factors affecting charged slides can impact immunoreactivity.
FDA ApprovedNew York Approved
Methodology
Immunoassay (IHC)
Biomarkers
Cytokeratin
Protein
LOINC Codes
- Order only; no result
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
Immunostain Technical Only Envelope
Collection Instructions
- Formalin-fixed, paraffin-embedded tissue block or - 2 unstained, positively charged slides (25 x 75 x 1-mm) per test ordered; sections 4-microns thick
Storage Instructions
Best practices for storage of positively charged slides: Minimize time slides are stored after being unpackaged, limit exposure to high humidity and heat, minimize exposure to plastics.
Causes for Rejection
Wet/frozen tissue, cytology smears, nonformalin fixed tissue, nonparaffin embedded tissue, noncharged slides, ProbeOn slides, Snowcoat slides will be rejected.