Keratin (OSCAR) Immunostain, Technical Component Only
Use
The OSCAR cytokeratin antibody covers a wide spectrum of molecular weights and is similar in expression pattern to CAM5.2, but with greater coverage of high molecular weight range such as squamous epithelium. It is diagnostically significant as antikeratin antibodies are typically used in panels to determine the cell lineage of poorly differentiated malignant tumors.
Special Instructions
This test includes only the technical performance of the stain with no pathologist interpretation provided. Technical component only stains should not be ordered with PATHC / Pathology Consultation. If ordered with PATHC, the technical component stains will be canceled. Any immunohistochemistry (IHC)/in situ hybridization (ISH) stain performed as part of the PATHC will be at the discretion of the reviewing pathologist at an additional charge. Attach the green 'Attention Pathology' address label and the pink Immunostain Technical Only label included in the kit to the transport container.
Limitations
This test does not include pathologist interpretation, only the technical performance of the stain. Interpretation should be performed in the context of the patient's clinical history and other diagnostic tests by a qualified pathologist. Age and environmental factors affecting charged slides can impact immunoreactivity.
FDA ApprovedNew York Approved
Methodology
Immunoassay (IHC)
Biomarkers
LOINC Codes
- Order only; no result
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
Immunostain Technical Only Envelope
Collection Instructions
- Formalin-fixed, paraffin-embedded tissue block or - 2 unstained, positively charged slides (25 x 75 x 1-mm) per test ordered; sections 4-microns thick
Storage Instructions
Best practices for storage of positively charged slides: Minimize time slides are stored after being unpackaged, limit exposure to high humidity and heat, minimize exposure to plastics.
Causes for Rejection
Wet/frozen tissue, cytology smears, nonformalin fixed tissue, nonparaffin embedded tissue, noncharged slides, ProbeOn slides, Snowcoat slides will be rejected.