Ketones, Urine
Use
The Ketones, Urine test is useful for screening for the presence of ketoacidosis. Ketones are produced during fat metabolism and are excreted in the urine. This test is particularly significant for patients with untreated or inadequately treated diabetes mellitus, as they are unable to efficiently utilize glucose, leading to the excretion of abnormal amounts of ketones in the urine. Increased ketones can also occur during physiological stress conditions such as fasting, starvation, pregnancy, strenuous exercise, fever, frequent vomiting, anorexia, and some inborn errors of metabolism.
Special Instructions
Ensure collection of a random urine specimen using a plastic urine container with no preservative added. The specimen should be refrigerated and is stable for up to 72 hours at this temperature.
Limitations
False positive results may occur with highly pigmented urine specimens or those containing large amounts of levodopa metabolites. Compounds such as mesna that contain sulfhydryl groups may also cause false positive results or an atypical color reaction. The results should be interpreted with caution, particularly in patients who are on medications that may interfere with the assay.
FDA ApprovedNew York Approved
Methodology
Automated Analyzer (Clinical Chemistry)
Biomarkers
LOINC Codes
- 50557-8
- 50557-8
Result Turnaround Time
1 day
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
20 mL
Minimum Volume
2 mL
Container
Plastic urine container
Collection Instructions
Collect a random urine specimen. No preservative.
Storage Instructions
Refrigerated
Causes for Rejection
No specimen should be rejected.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 72 hours |