Ki-67(MIB-1), Gastrointestinal/Pancreatic Neuroendocrine Tumors, Quantitative Immunohistochemistry, Manual
Use
Ki-67(MIB-1 clone) is a monoclonal antibody that reacts with cells undergoing DNA synthesis by binding to the Ki-67 antigen, a marker expressed only in proliferating cells. In paraffin-embedded tissue specimens, Ki-67(MIB-1) analysis can provide prognostic information on tumor proliferation. The test is useful for determining the proliferation of tumor cells in patients diagnosed with neuroendocrine tumors of the pancreas or gastrointestinal tract, including metastases.
Special Instructions
This is not an orderable test. Order PATHC / Pathology Consultation, where the consultant will determine the need for special stains. Pathologist’s contact information and the accompanying pathology report stating the final or preliminary diagnosis are required.
Limitations
Results must be interpreted in the context of clinical findings and other laboratory data. The paraffin block analyzed must accurately represent the patient's tumor.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
LOINC Codes
- 29593-1
- 29593-1
- 19139-5
- 81178-6
- 62364-5
- 80398-1
Result Turnaround Time
4-6 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
Pathology Packaging Kit
Collection Instructions
Submit formalin-fixed, paraffin-embedded tissue block containing neuroendocrine tumor. Acceptable: 2 unstained sections on charged slides cut at 4 microns <1 month ago, fixed in 10% neutral buffered formalin.
Storage Instructions
Attach the green 'Attention Pathology' address label to the transport container before sending.
Causes for Rejection
No specimen should be rejected.