Melan A (MART-1) Immunostain, Technical Component Only
Use
Melanoma antigen recognized by T cells, or Melan-A (MART-1), is a protein associated with the endoplasmic reticulum and melanosomes. This test aids in the identification of melanoma as Melan A is a sensitive and specific marker for diagnosing melanoma. It is also found in other tumors of melanocytic origin, such as clear cell sarcoma, melanotic neurofibroma, and others.
Special Instructions
Not provided.
Limitations
The test does not provide pathologist interpretation. The age of a cut paraffin section can affect immunoreactivity, with stability varying among antigens. Best practice is for paraffin sections to be cut within 6 weeks. Slide charge can be affected by environmental factors, altering staining. Unsuitable slides may result in inconsistent results.
FDA ApprovedNew York Approved
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
Immunostain Technical Only Envelope
Collection Instructions
Formalin-fixed, paraffin-embedded tissue block or 2 unstained, positively charged glass slides (25- x 75- x 1-mm) per test ordered; sections 4-microns thick.
Causes for Rejection
Wet/frozen tissue, cytology smears, nonformalin fixed tissue, nonparaffin embedded tissue, noncharged slides, ProbeOn slides, Snowcoat slides