MUM-1/IRF4 Immunostain, Bone Marrow, Technical Component Only
Use
This test aids in the identification of hematolymphoid neoplasms and melanomas. The MUM-1 protein, expressed by the IRF4 gene, is present in a subset of B cells, plasma cells, and activated T cells. It's also found in various hematolymphoid neoplasms and some melanomas. This test is primarily used for cases involving suspected hematolymphoid malignancies or to differentiate among similar tumor types.
Special Instructions
This test includes only the technical performance of the IHC stain; no pathologist interpretation is provided. The test should not be ordered with PATHC / Pathology Consultation as it will be canceled. Ensure to attach the green pathology address label and pink Immunostain Technical Only label to the container.
Limitations
This test is optimized for B5-fixed, decalcified, paraffin-embedded bone marrow specimens. It does not include pathologist interpretation, which must be ordered separately if required. Glass slide quality can affect staining, and slides should be stored to minimize humidity and heat exposure.
FDA ApprovedNew York Approved
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
Immunostain Technical Only Envelope
Storage Instructions
Ambient (preferred) or refrigerated.
Causes for Rejection
Wet/frozen tissue, cytology smears, nonformalin fixed tissue, nonparaffin embedded tissue, noncharged slides, ProbeOn slides, Snowcoat slides.