OLIG2 Immunostain, Technical Component Only
Use
This test is useful for distinguishing gliomas from neurocytomas and ependymomas. OLIG2 is a transcription factor involved in oligodendrocyte and motor neuron differentiation. Its expression remains present in mature glial cells and is involved in glioblastoma progression due to its repression of the p53 tumor suppressor pathway.
Special Instructions
Not provided.
Limitations
The test does not include pathologist interpretation; any interpretation needed should be done by a qualified pathologist with consideration of the patient's history and other diagnostic tests. There is a caution regarding paraffin section age which can affect immunoreactivity, and best practice is to use sections cut within 6 weeks.
FDA ApprovedNew York Approved
Methodology
Immunoassay (IHC)
Biomarkers
OLIG2
Protein
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
Immunostain Technical Only Envelope
Causes for Rejection
Wet/frozen tissue, cytology smears, nonformalin fixed tissue, nonparaffin embedded tissue, noncharged slides, ProbeOn slides, Snowcoat slides