Ovomucoid, IgE, Serum

Casandra

Casandra Test Code MC38377Version 1 (DRAFT)

Performing Lab

Lab Mayo Clinic LabLab Test ID OVMUCPT Code 86008

Ovomucoid, IgE, Serum

Clinical Use

Use

This test is useful for establishing a diagnosis of an allergy to ovomucoid, a major allergen found in egg whites. It helps in defining the allergen responsible for allergic reactions including those causing anaphylactic episodes. The test is particularly useful for identifying allergens prior to starting immunotherapy and can be used to investigate the specificity of allergic reactions to insect venom allergens, drugs, or chemical allergens. It measures IgE antibodies in serum, which are indicative of the immune response to allergens associated with allergic diseases.

Special Instructions

If not ordering electronically, complete, print, and send an Allergen Test Request (T236) with the specimen. The test measures specific IgE from the patient's serum reacting with the allergen, covalently coupled to an ImmunoCAP. The test days are Monday through Friday, and the report is usually available the same day, or within 1 to 3 days.

Limitations

Testing for IgE antibodies is not useful in patients who have previously been treated with immunotherapy to determine if residual clinical sensitivity exists. It is also less useful in patients where the medical management does not rely on identifying the specific allergen. False-positive results may occur in patients with markedly elevated serum IgE (>2500 kU/L) due to nonspecific binding to allergen solid phases. Some individuals with minor sensitivities may still have measurable IgE levels, thus results should be interpreted within the clinical context.

Test Details

FDA Approved