Peanut, IgE, Serum
Use
This test is useful for establishing a diagnosis of an allergy to peanuts, defining the allergen responsible for symptoms, and identifying allergens responsible for allergic responses or anaphylactic episodes. It helps confirm sensitization prior to immunotherapy and investigates the specificity of allergic reactions, including those to insect venom, drugs, or chemical allergens. It is not useful for determining if residual sensitivity exists in patients treated with immunotherapy or when medical management does not depend on identifying allergen specificity.
Special Instructions
For ordering, if not done electronically, complete and send the Allergen Test Request (T236) form with the specimen. Proper specimen handling is required: centrifuge and aliquot serum into a plastic vial. Preferred collection container is a serum gel tube, but a red top is acceptable.
Limitations
Negative results do not completely exclude the possibility of allergic responses to peanuts, and clinical correlation is recommended. Positive IgE results indicate sensitization but are not diagnostic of peanut allergy. Elevated concentrations of total peanut IgE do not always correlate with clinical symptoms. False positives can occur in patients with elevated serum IgE due to non-specific binding.
Methodology
Immunoassay (FEIA)
Biomarkers
LOINC Codes
- 6206-7
- 6206-7
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL for every 5 allergens requested
Minimum Volume
For 1 allergen: 0.3 mL
Container
Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Causes for Rejection
Gross hemolysis, lipemia, icterus
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
| Refrigerated | 14 days |
| Frozen | 90 days |
