Phosphatidylethanol Confirmation, Blood
Use
Phosphatidylethanol (PEth) is a direct biomarker for alcohol (ethanol) intake. It is used to verify abstinence or detect ethanol usage, especially in liver transplant candidates and patients. PEth levels in blood correlate with the amount of alcohol consumed over the past 2 weeks and can be detected up to 2 to 4 weeks after alcohol intake.
Special Instructions
Do not use alcohol to clean the venipuncture site; use Betadine or Povidone Iodine instead. Collect blood in tubes smaller than 10 mL and send entire whole blood specimen in original EDTA tube without centrifuging or aliquoting. Complete and send the appropriate requisition form if not ordering electronically.
Limitations
PEth levels should be interpreted cautiously as numerous factors, such as biology and alcohol consumption habits, may influence results. Results should be considered in conjunction with clinical and behavioral data as they alone do not indicate alcohol misuse.
New York Approved
Methodology
Mass Spectrometry (LC-MS/MS)
Biomarkers
LOINC Codes
- 101506-4
- 97607-6
- 97606-8
- 69050-3
Result Turnaround Time
2-5 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
1 mL
Minimum Volume
0.5 mL
Container
Lavender top (EDTA)
Collection Instructions
Do not use alcohol to clean the arm. Use Betadine or Povidone Iodine. Draw blood in tubes smaller than 10 mL if possible. Do not centrifuge. Send whole blood specimen in original tube. Do not aliquot.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 28 days |