Use

This test is useful for serial monitoring of CD4 T-cell count in HIV-positive patients, and for follow-up and diagnostic evaluation of primary immunodeficiencies such as severe combined immunodeficiency. It is also employed in immune monitoring following immunosuppressive therapy for transplantation, autoimmunity, and other immunological conditions. It serves as a screening tool for identifying gross quantitative anomalies in lymphocyte subsets in infections or malignancies, and assists in the diagnosis of chronic lymphocytic leukemia by quantifying circulating B cells.