Rabbit Urine Proteins, IgE, Serum
Use
This test is useful for establishing the diagnosis of an allergy to rabbit urine proteins by identifying IgE antibodies in serum. It helps define allergens responsible for eliciting allergic signs and symptoms, confirming sensitization before immunotherapy, and investigating the specificity of allergic reactions to insect venom allergens, drugs, or chemical allergens. IgE testing is not useful in patients previously treated with immunotherapy for residual clinical sensitivity or when medical management does not depend on allergen specificity.
Special Instructions
For ordering, if not electronically, complete and send an Allergen Test Request form (T236) with the specimen. Centrifuge and aliquot serum into a plastic vial. Use 0.5 mL for every 5 allergens requested. When testing for a single allergen, 0.3 mL is required. If more than one allergen is tested, use the formula (0.05 mL x number of allergens) + 0.25 mL for volume calculation.
Limitations
The test may yield false positives in patients with elevated serum IgE (>2500 kU/L) due to nonspecific binding. Some individuals with insignificant allergen sensitivity may have measurable IgE levels, requiring clinical context interpretation. The test does not determine residual sensitivity after immunotherapy or for cases where allergen identification is non-essential for management.
Methodology
Immunoassay (FEIA)
Biomarkers
LOINC Codes
- 10961-1
- 10961-1
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL
Minimum Volume
For 1 allergen: 0.3 mL
Container
Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Causes for Rejection
Gross hemolysis and gross lipemia conditions are acceptable.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 90 days |
