Use

This test is useful for the interpretation of results for the red blood cell enzyme evaluation, identifying defects of red cell enzyme metabolism, and evaluating patients with Coombs-negative hemolytic anemia. Erythrocyte enzyme deficiencies are inherited causes of hemolytic anemia. Most deficiencies result in chronic nonspherocytic hemolytic anemia of variable severity. The test is a consultative evaluation of red cell enzyme activity as a potential cause of early red cell destruction.