Ro52 Antibody, IgG, Serum
Use
Evaluating patients at risk for connective tissue disease with or without interstitial lung disease. Differentiating single vs double positivity for Ro52 and Ro60 antibodies in combination with anti-Ro60. The SS-A/Ro is part of the Ro/La antigenic complex, prevalent among autoimmune diseases such as Sjogren’s syndrome, systemic lupus erythematosus, systemic sclerosis, idiopathic inflammatory myopathy, rheumatoid arthritis, and primary biliary cholangitis. Presence of anti-Ro52 and anti-Ro60 antibodies may indicate certain autoimmune diseases like systemic lupus erythematosus and Sjogren’s syndrome.
Special Instructions
Not provided.
Limitations
Results should be interpreted with clinical findings and other laboratory testing. Tests should not exclusively be relied upon for diagnosing connective tissue disease, systemic lupus erythematosus, Sjogren's syndrome, systemic sclerosis, or idiopathic inflammatory myopathy. Some antibodies specific for SSA 52 may not be detected due to masking of target epitopes.
FDA ApprovedNew York Approved
Methodology
Immunoassay (CLIA)
Biomarkers
Ro52
Protein
LOINC Codes
- 53017-0 - ENA SS-A 52kD Ab Ser-aCnc
- 53017-0 - ENA SS-A 52kD Ab Ser-aCnc
Result Turnaround Time
2-8 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL
Minimum Volume
0.4 mL
Container
Plastic vial
Collection Instructions
Centrifuge and aliquot serum into plastic vial
Causes for Rejection
Gross hemolysis, Gross lipemia
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 21 days |