Rubella Antibodies, IgG, Serum
Use
Rubella Antibodies, IgG, Serum is useful for determining immune status to the rubella virus. It can indicate prior exposure or vaccination against rubella by detecting the presence of IgG-class antibodies, suggesting immunity. The test plays a critical role in assessing immunity in individuals, particularly those who may be at risk of rubella exposure or are planning pregnancy, as primary in-utero rubella infections can lead to severe fetal complications such as congenital rubella syndrome.
Special Instructions
If not ordering electronically, complete and submit the Infectious Disease Serology Test Request form along with the specimen. Ensure that serum is collected, centrifuged, and aliquoted into a plastic vial for submission. Continual monitoring for potential interfering substances, such as blood products received by the patient, is advised.
Limitations
The presence of IgG-class antibodies does not exclude the possibility of a recent or ongoing infection. Testing for IgM-class antibodies is recommended if acute infection is suspected. Samples collected early during infection may yield negative IgG results. False positives may occur in individuals recently exposed to blood products but not immunized.
FDA ApprovedNew York Approved
Methodology
Immunoassay (Multiplex Flow Immunoassay)
Biomarkers
LOINC Codes
- 5334-8
- 40667-8
- 5334-8
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL
Minimum Volume
0.4 mL
Container
Serum gel (preferred), Red top (acceptable), Plastic vial for submission
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Storage Instructions
Refrigerated (preferred) up to 14 days, or Frozen up to 14 days.
Causes for Rejection
Gross hemolysis, gross lipemia, gross icterus, heat-inactivated specimen
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 14 days |