Salmon, IgE, Serum
Use
The Salmon, IgE, Serum test is used to establish a diagnosis of an allergy to salmon by defining the allergen responsible for eliciting signs and symptoms. It is helpful in identifying allergens responsible for allergic responses and/or anaphylactic episodes, confirming sensitization prior to beginning immunotherapy, and investigating the specificity of allergic reactions to various allergens such as insect venom, drugs, or chemical allergens. However, it is not useful in patients previously treated with immunotherapy for determining if residual clinical sensitivity exists or in patients where medical management does not depend on allergen specificity identification.
Special Instructions
For ordering, complete the Allergen Test Request form (T236) and include it with the specimen if not ordering electronically. The specimen should be collected in a serum gel container if available or a red top if necessary, then aliquoted into a plastic vial after centrifugation.
Limitations
The test may produce false-positive results for IgE antibodies in patients with markedly elevated serum IgE levels, due to nonspecific binding to allergen solid phases. Additionally, individuals with clinically insignificant sensitivity may show measurable levels of IgE antibodies, requiring results to be interpreted in the clinical context.
New York Approved
Methodology
Immunoassay (Fluorescence Enzyme Immunoassay (FEIA))
Biomarkers
LOINC Codes
- 6237-2
- 6237-2
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL for every 5 allergens requested
Minimum Volume
0.3 mL for 1 allergen, more for multiple allergens with an additional 0.25 mL deadspace
Container
Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Causes for Rejection
Grossly hemolyzed or lipemic samples are acceptable.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 90 days |