Selenium, Blood
Use
This test is useful for the assessment of tissue stores of selenium, an essential element needed by humans and animals. Selenium is used in various applications like photographic devices, gun bluing, plastics, paints, and nutritional supplements. By measuring selenium concentrations in whole blood, the test can provide insight into an individual's selenium status and overall health, given that selenium is a crucial component of several vital biological processes.
Special Instructions
The test is performed using Triple-Quadrupole Inductively Coupled Plasma Mass Spectrometry (ICP-MS) to ensure accurate measurement of selenium levels. A specimen should not be collected for at least 96 hours if gadolinium- or iodine-containing contrast media has been administered, as these substances can interfere with metal tests based on ICP-MS technology.
Limitations
Selenium concentration values should be interpreted in relation to the clinical scenario, including symptoms, physical findings, and other diagnostic results. Misinterpretation of the test results can occur without considering the entire clinical context. Additionally, improper specimen collection and handling, inappropriate test selection, or the presence of interfering substances like gadolinium and iodine contrast media can affect test accuracy.
New York Approved
Methodology
Mass Spectrometry (ICP-MS)
Biomarkers
LOINC Codes
- 5722-4
- 5722-4
Result Turnaround Time
2-8 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
0.8 mL
Minimum Volume
0.3 mL
Container
Royal blue-top BD vacutainer with EDTA blood collection tube
Collection Instructions
See Metals Analysis Specimen Collection and Transport for complete instructions. Send whole blood specimen in original tube. Do not aliquot.
Patient Preparation
High concentrations of gadolinium and iodine can interfere with test results from ICP-MS based tests. Avoid specimen collection for at least 96 hours post administration of such contrast media.
Causes for Rejection
Microtainer
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 28 days |
| Refrigerated | 28 days |
| Frozen | 28 days |