Use

Detecting septin-7 IgG by cell-binding assay using serum specimens. The presence of septin-7 IgG is associated with various neurological phenotypes, including encephalopathy, myelopathy, encephalomyelopathy, painful myelopolyradiculopathy, and episodic ataxia. It is also associated with psychiatric symptoms and cancer. The test helps confirm the diagnosis of autoimmune disease of the central nervous system when septin-7 IgG is detected via cell-binding assay.