Spirochete Immunostain, Technical Component Only
Use
This test is useful for identifying spirochete organisms in cases of intestinal spirochetosis, as well as cases of syphilis caused by infection with the spirochete Treponema pallidum. It aids in the diagnosis of diseases caused by these spirochetes through the detection of antigens using immunohistochemical staining methods.
Special Instructions
This test includes only the technical performance of the stain and does not provide pathologist interpretation. Pathology consultation should not be ordered with this technical component, as any such stains will be canceled. For interpretation, separate pathology consultation is required. Shipping instructions include attaching specific labels to the transport container.
Limitations
Contamination and cross-reactivity with other microorganisms may lead to nonspecific staining. Age of paraffin sections can affect immunoreactivity, and the stability of these sections varies widely. The best practice is to cut sections within 6 weeks for optimal performance. False positives may occur due to cross-reactivity, and interpretation should be done in context with clinical and serologic findings.
FDA ApprovedNew York Approved
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
Immunostain Technical Only Envelope
Storage Instructions
Ambient temperature preferred; alternatively refrigerated.
Causes for Rejection
Wet/frozen tissue, cytology smears, nonformalin fixed tissue, nonparaffin embedded tissue, noncharged slides, ProbeOn slides, Snowcoat slides.