Streptococcus pneumoniae Antigen, Spinal Fluid
Use
Streptococcus pneumoniae is the most frequently encountered bacterial agent of community-acquired pneumonia and can also cause bacterial meningitis. Rapid diagnosis of pneumococcal meningitis is crucial due to the associated significant morbidity and mortality. Antigen testing aids in the diagnosis when empirical antibiotics are being considered prior to culture confirmation. It provides a rapid diagnosis, aiding in the early management of pneumococcal infections.
Special Instructions
Not provided.
Limitations
A negative result does not exclude Streptococcus pneumoniae infection. A diagnosis of Streptococcus pneumoniae infection must consider all test results, culture results, and the clinical presentation of the patient. Streptococcus pneumoniae vaccine may cause false-positive results, particularly in patients who received the vaccine within 5 days prior to specimen collection. This assay has not been validated for use with body fluids other than urine or cerebrospinal fluid. Performance has not been established for patients on antibiotic treatment for more than 24 hours.
FDA ApprovedNew York Approved
Methodology
Immunoassay (Immunochromatographic Membrane Assay)
Biomarkers
Streptococcus pneumoniae
Microorganism
LOINC Codes
- 20489-1 - S pneum Ag CSF Ql
- 20489-1 - S pneum Ag CSF Ql
Result Turnaround Time
1 day
Related Documents
For more information, please review the documents below
Specimen
Cerebrospinal Fluid
Volume
1 mL
Minimum Volume
0.5 mL
Container
Sterile vial
Collection Instructions
Submit specimen collected in vial 2 if possible. If not, note the vial from which the aliquot was obtained.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 14 days |