Streptococcus pneumoniae IgG Antibodies, 23 Serotypes, Serum
Use
This test is used for assessing the IgG antibody response to active immunization with both nonconjugated and conjugated pneumococcal vaccines of various valences. It helps in determining an individual's ability to produce an antibody response to polysaccharide antigens, which is crucial for evaluating humoral or combined immunodeficiencies. The test can detect responses to vaccines such as the 23-valent PPSV23, and also the newer conjugated vaccines (PCV13, PCV15, PCV20) that are used prominently in different age groups and patient conditions.
Special Instructions
Not provided.
Limitations
The test does not define protective concentrations of IgG antibodies for any serotype, therefore functional antibody capacity (opsonization efficiency) is not evaluated. The immune response following vaccination can be influenced by multiple factors including age, immune status, past infections, and carrier state. Quantitative measures provided by this test do not reflect functional antibody activity.
New York Approved
Methodology
Immunoassay (Multiplex Protein Panel)
Biomarkers
IgG Antibodies
Protein
LOINC Codes
- 42366-5 - S pneum 23 serotypes IgG Pnl Ser-mCnc
- 85954-6 - S pneum Da 1 IgG Ser-mCnc
- 86039-5 - S pneum Da 2 IgG Ser-mCnc
- 86080-9 - S pneum Da 3 IgG Ser-mCnc
- 86107-0 - S pneum Da 4 IgG Ser-mCnc
- 86130-2 - S pneum Da 5 IgG Ser-mCnc
- 86147-6 - S pneum Da 8 IgG Ser-mCnc
- 86169-0 - S pneum Da 9N IgG Ser-mCnc
- 85977-7 - S pneum Da 12F IgG Ser-mCnc
- 85991-8 - S pneum Da 14 IgG Ser-mCnc
- 86009-8 - S pneum Da 17F IgG Ser-mCnc
- 86024-7 - S pn Da sero 19F IgG Ser-mCnc
- 86045-2 - S pneum Da 20A IgG Ser-mCnc
- 86052-8 - S pneum Da 22F IgG Ser-mCnc
- 86064-3 - S pneum Da 23F IgG Ser-mCnc
- 27118-9 - S pneum Da 6B IgG Ser-mCnc
- 86098-1 - S pneum Da 10A IgG Ser-mCnc
- 86122-9 - S pneum Da 11A IgG Ser-mCnc
- 25296-5 - S pneum Da 7F IgG Ser-mCnc
- 40973-0 - S pneum Da 15B IgG Ser-mCnc
- 27395-3 - S pneum Da 18C IgG Ser-mCnc
- 40974-8 - S pneum Da 19A IgG Ser-mCnc
- 30153-1 - S pneum Da 9V IgG Ser-mCnc
- 40969-8 - S pneum Da 33F IgG Ser-mCnc
- 69048-7 - Immunologist review
Result Turnaround Time
4-6 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL
Minimum Volume
0.4 mL
Container
Plastic vial
Collection Instructions
Centrifuge and aliquot serum into plastic vial
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 21 days |
| Frozen | 21 days |