Sunflower, IgE, Serum
Use
The Sunflower, IgE test is useful for establishing the diagnosis of an allergy to sunflower seeds and identifying the specific allergen responsible for eliciting signs and symptoms. It helps in confirming sensitization prior to immunotherapy and investigating allergic reactions to insect venom allergens, drugs, or chemical allergens. This test detects IgE antibodies associated with allergic diseases, and its results are significant for patients demonstrating clinical manifestations such as eczema, rhinitis, and asthma.
Special Instructions
This test should not be used to determine residual clinical sensitivity in patients treated with immunotherapy or where medical management does not depend on identification of allergen specificity. When ordering manually, complete the Allergen Test Request (T236) form and include it with the specimen. The required specimen is serum, collected preferably in a serum gel tube or a red top tube. Centrifuge and aliquot into a plastic vial before submission.
Limitations
The test may yield false-positive results in patients with markedly elevated serum IgE (>2500 kU/L) due to nonspecific binding. Additionally, measurable levels of IgE in serum might be observed in individuals with clinically insignificant sensitivity to allergens. Care must be taken to interpret results within the clinical context, considering that immediate hypersensitivity diseases involve the release of proinflammatory mediators from IgE-sensitized effector cells.
Methodology
Immunoassay (Fluorescence Enzyme Immunoassay (FEIA))
Biomarkers
LOINC Codes
- 7726-3
- 7726-3
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL for every 5 allergens requested
Minimum Volume
0.3 mL for 1 allergen
Container
Serum gel or Red top tube, submission in a Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 90 days |
