Syphilis IgG Enzyme Immunoassay, Serum
Use
This test is an aid in the diagnosis of infection with Treponema pallidum, the causative agent of syphilis. It is especially useful for routine prenatal screening to assess for recent or past infection. The test employs the reverse screening algorithm, starting with an automated treponemal-specific assay. If positive, further testing is required to determine disease state.
Special Instructions
This test should not be used for diagnosing congenital syphilis and is not offered as a screening or confirmatory test for blood donor specimens. Clinical context and history should be considered alongside results for accurate interpretation.
Limitations
Despite active syphilis infection, serologic tests may be negative in immunocompromised patients such as those with AIDS. In very early primary syphilis, serologic tests may yield negative results. Treponemal tests may remain positive for life, even after successful treatment, necessitating further testing to distinguish between active, treated, or late-stage infection.
FDA ApprovedNew York Approved
Methodology
Immunoassay (EIA)
Biomarkers
LOINC Codes
- 47238-1
- 47238-1
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.6 mL
Minimum Volume
0.5 mL
Container
Plastic vial
Collection Instructions
Centrifuge and aliquot serum into plastic vial.
Causes for Rejection
Gross hemolysis, gross lipemia, heat-inactivated specimen
Stability Requirements
| Temperature | Period |
|---|---|
| Frozen | 14 days |