Targeted Benzodiazepine Screen, Random, Urine
Use
Benzodiazepines are used to treat a range of disorders, from anxiety to seizures, and pain management. They carry a high risk for abuse and diversion, necessitating compliance monitoring through urine drug tests. Traditional benzodiazepine immunoassays often lack cross-reactivity with all benzodiazepines, which can result in negative screens for patients taking clonazepam or lorazepam despite compliance. This targeted screen offers a more sensitive and specific test to detect compliance with common benzodiazepines by identifying both the parent drug and its metabolites in urine.
Special Instructions
Not provided.
Limitations
This test is not intended for employment-related testing. The absence of expected benzodiazepines or their metabolites could indicate noncompliance, inappropriate timing of specimen collection related to drug administration, poor drug absorption, diluted or adulterated urine, or limitations of testing. There may be a need to contact the laboratory for specific drug quantification within two weeks if concentrations are required.
Methodology
Mass Spectrometry (LC-MS/MS)
Biomarkers
LOINC Codes
- 94117-9 - Benzodiazepines Pnl Ur Scn
- 94116-1 - Alpraz Ur Ql Scn
- 19325-0 - A-OH Alpraz Ur Ql Scn
- 94115-3 - A-OH Alpraz gluc Ur Ql Scn
- 19385-4 - Chlordiazep Ur Ql Scn
- 94114-6 - cloBAZam Ur Ql Scn
- 94113-8 - Norclobazam Ur Ql Scn
- 19399-5 - clonazePAM Ur Ql Scn
- 94112-0 - 7Aminoclonazepam Ur Ql Scn
- 19443-1 - diazePAM Ur Ql Scn
- 19624-6 - Nordiazepam Ur Ql Scn
- 19466-2 - Flunitrazepam Ur Ql Scn
- 94111-2 - 7Aminoflunitrazepam Ur Ql Scn
- 19474-6 - Flurazepam Ur Ql Scn
- 94110-4 - 2-OH-Ethylfluraz Ur Ql Scn
- 19520-6 - LORazepam Ur Ql Scn
- 94109-6 - LORazepam glucuronide Ur Ql Scn
- 19585-9 - Midazolam Ur Ql Scn
- 94108-8 - 1OH-midazolam Ur Ql Scn
- 19638-6 - Oxazepam Ur Ql Scn
- 94107-0 - Oxazepam glucuronide Ur Ql Scn
- 19678-2 - Prazepam Ur Ql Scn
- 19698-0 - Temazepam Ur Ql Scn
- 94106-2 - Temazepam glucuronide Ur Ql Scn
- 19714-5 - Triazolam Ur Ql Scn
- 94105-4 - A-OH-triazolam Ur Ql Scn
- 94104-7 - Zolpidem Ur Ql Scn
- 94103-9 - Zolpidem phenyl-4-carb Ur Ql Scn
- 69050-3 - Toxicologist review
- 29305-0 - Medication prescribed
Result Turnaround Time
3-4 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
1 mL
Minimum Volume
0.5 mL
Container
Plastic, 5-mL tube
Collection Instructions
Collect a random urine specimen. No preservative.
Causes for Rejection
Gross hemolysis, Gross icterus
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 72 hours |
| Refrigerated | 14 days |
| Frozen | 28 days |
