Targeted Opioid Screen, Random, Urine

Casandra

Casandra Test Code MC11283Version 1 (DRAFT)

Performing Lab

Lab Mayo Clinic LabLab Test ID TOSUCPT Codes 0481, 80364

Targeted Opioid Screen, Random, Urine

Clinical Use

Use

This test is useful for determining compliance or identifying illicit opioid drug use using urine specimens. It is not intended for employment-related testing. Opioids are a large class of medications commonly used to relieve pain or manage opioid abuse and include drugs such as buprenorphine, codeine, fentanyl, hydrocodone, hydromorphone, methadone, morphine, oxycodone, oxymorphone, tapentadol, and tramadol. These medications bind to opioid receptors in the brain, spinal cord, gastrointestinal tract, and other organs.

Special Instructions

This test uses high-resolution accurate mass spectrometry to identify 33 different opioids and metabolites. It offers lower detection limits than previous screens and can detect 'spiked' samples. No additional testing is required if the parent drug or metabolites found are consistent with the patient's prescribed medications.

Limitations

The test does not hydrolyze the urine sample and looks for both parent drugs and metabolites. The detection window for most opioids in urine is approximately 1 to 3 days, with longer detection times for some compounds such as methadone. Positive results are reported with qualitative 'Present' results, and cutoff concentrations are provided for specific opioids and their metabolites. A second analytical technique can be requested at an additional charge if specific drug concentration is needed.

Test Details

New York Approved