Terminal Deoxynucleotidyl Transferase (TdT) Immunostain, Technical Component Only
Use
The test is useful for the classification of leukemias or lymphomas. Terminal deoxynucleotidyl transferase (TdT) is a nuclear enzyme involved in the addition of nucleotides to the termini of DNA strands. It is expressed in cortical thymocytes and immature hematopoietic stem cells, making it useful in diagnosing lymphoblastic lymphoma or leukemia and can also be expressed in acute myeloid leukemias.
Special Instructions
This test only includes the technical performance of the stain; no pathologist interpretation is provided. Technical component only stains should not be ordered with pathology consultation (PATHC). If ordered with PATHC, the technical component stains will be canceled.
Limitations
The test does not include pathologist interpretation, only the technical performance of the stain. Interpretations should be performed in the context of the patient's clinical history and other diagnostic tests by a qualified pathologist. Age of a cut paraffin section can affect immunoreactivity, and stability thresholds vary widely and are antigen dependent. Only stained slides will be verified for immunoreactivity.
FDA ApprovedNew York Approved
Methodology
Immunoassay (IHC)
Biomarkers
LOINC Codes
- Order only;no result
- Bill only; no result
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
Immunostain Technical Only Envelope
Collection Instructions
Attach the green 'Attention Pathology' label and pink Immunostain Technical Only label to the transport container.
Causes for Rejection
Wet/frozen tissue, cytology smears, nonformalin fixed tissue, nonparaffin embedded tissue, noncharged slides, ProbeOn slides, Snowcoat slides
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Ambient (preferred) |
| Refrigerated | Refrigerated |