Thallium/Creatinine Ratio, Random, Urine
Use
Detecting toxic thallium exposure in random urine specimen. Thallium is odorless, tasteless, and found in trace amounts in the earth's crust, used in electronic manufacturing and previously in rodenticides. Exposure may occur via ingestion (food, smoking). Acute ingestion can lead to vomiting, diarrhea, sensorimotor polyneuropathy, and alopecia within about a week; other symptoms include gastrointestinal, myalgia, hypertension, cardiac, and liver injury. Most thallium is excreted in urine, detectable as early as one hour post exposure and up to two months thereafter.
Special Instructions
For specimen collection: if gadolinium- or iodine-containing contrast media has been administered, do not collect a specimen for 96 hours. Use clean plastic urine collection container with no metal cap or glued insert; supplies include Urine Tubes, 10 mL (T068). Submission in plastic 10‑mL urine tube or a clean plastic aliquot container with no metal cap or glued insert. Refer to 'Metals Analysis Specimen Collection and Transport' for complete instructions.
Limitations
No significant cautionary statements were provided regarding analytical or interpretive limitations.
New York Approved
Methodology
Mass Spectrometry (ICP‑MS)
Biomarkers
LOINC Codes
- 13469-2
- 2161-8
- 13469-2
Result Turnaround Time
2-5 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
7 mL
Minimum Volume
1.3mL
Container
Clean, plastic urine collection container with no metal cap or glued insert; submission container: plastic, 10‑mL urine tube or clean plastic aliquot container with no metal cap or glued insert
Collection Instructions
Collect a random urine specimen. If gadolinium- or iodine-containing contrast media has been administered, delay collection for 96 hours.
Causes for Rejection
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 28 days |
| Frozen | 28 days |