Use

This test is useful for explaining unusual thyroxine (T4), free T4, and thyroxine-binding globulin test results that do not correlate with the patient's clinical presentation. It is also helpful in detecting the presence of aberrant thyroxine-binding proteins, such as abnormal forms of albumin and prealbumin, and detecting selective deficiency of one of the thyroxine-binding proteins. Additionally, it can detect antibodies to T4 and serve as an adjunct in diagnosing patients with high T4 concentration due to peripheral hormone resistance by ruling out thyroxine-binding abnormalities.