Trichoderma viride, IgE, Serum
Use
This test is useful for establishing a diagnosis of an allergy to Trichoderma viride by identifying the specific allergen responsible for eliciting signs and symptoms. It aids in confirming sensitization prior to beginning immunotherapy and investigating the specificity of allergic reactions to insect venom, drugs, or chemical allergens. Testing for IgE antibodies is not useful for assessing residual clinical sensitivity in patients who have previously undergone immunotherapy or in cases where medical management does not require the identification of allergen specificity.
Special Instructions
For a listing of allergens available for testing, refer to the Allergens - Immunoglobulin E (IgE) Antibodies document. Specimens should be collected using a serum gel container as preferred, with the red top as acceptable. The specimen volume required is 0.5 mL for every 5 allergens requested, with specific collection and handling instructions to aliquot serum into a plastic vial after centrifugation.
Limitations
The test is not useful for identifying residual clinical sensitivity in patients who have completed immunotherapy or in managing allergic disease without the need for allergen specificity. False-positive results may occur in patients with markedly elevated serum IgE (>2500 kU/L) due to nonspecific binding. Proper specimen handling and context-specific interpretation of results are crucial due to variable IgE levels among individuals with clinically insignificant sensitivities.
Methodology
Immunoassay (FEIA)
Biomarkers
LOINC Codes
- 6267-9
- 6267-9
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL for every 5 allergens requested
Minimum Volume
0.05 mL x number of allergens + 0.25 mL deadspace
Container
Serum gel (preferred), Red top (acceptable), Plastic vial (submission)
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 90 days |
